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Search Results for " c-reactive protein "
Targets Recommended: Others

13

抑制剂 & 化合物

3

天然产物

16

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
TP1676L C-Reactive Protein (CRP) 201-206 acetate

C-Reactive Protein (CRP) 201-206 acetate(130348-99-1 free base)

Others Others
C-Reactive Protein (CRP) 201-206 acetate (C-Reactive Protein )(130348-99-1 free base) 是 C-反应蛋白的 201-206 片段。 C-反应蛋白 (CRP) 醋酸盐是炎症的原型标志物,是心血管风险标志物,可能促进动脉粥样硬化形成。
TP1516L C-Reactive Protein (CRP) 77-82 acetate

C-Reactive Protein (CRP) 77-82 acetate(130349-01-8 free base)

Others Others
C-Reactive Protein (CRP) 77-82 acetate(130349-01-8 free base) 是 C-反应蛋白的 77-82 片段。 C-反应蛋白 (CRP) 是炎症的原型标志物,是心血管风险标志物,可能促进动脉粥样硬化。C-反应蛋白 (CRP) 是一种环状(环状)五聚体蛋白,存在于血浆中,其循环浓度炎症反应而升高。它是一种肝脏来源的急性期蛋白,在巨噬细胞和 T 细胞分泌 IL-6 后会增加。
TP1592L C-Reactive Protein (CRP) 174-185 acetate

C-Reactive Protein (CRP) 174-185 acetate(160369-86-8 free base)

Others Others
C-Reactive Protein (CRP) 174-185 acetate(160369-86-8 free base) 是一种急性期血清蛋白,可响应炎性细胞因子而合成,在动物中产生抗肿瘤作用。片段 CRP (174-185) (RS-83277) 通过显着增强体外人单核细胞和肺泡巨噬细胞的杀肿瘤活性显示出相似的活性。
TP1676 C-Reactive Protein (CRP) (201-206)

C-Reactive Protein (CRP) 201-206

Others Others
C-Reactive Protein (CRP) (201-206) 是 C-反应蛋白的 201-206 片段。其中C-反应蛋白 (CRP) 是炎症的原型标志物,是心血管风险标志物,可能促进动脉粥样硬化形成。
TP1592 C-Reactive Protein (CRP) (174-185)

C-Reactive Protein (CRP) 174-185

CRP, an acute phase serum protein synthesized in response to inflammatory cytokines, produces antitumor effects in animals. The fragment CRP (174-185) (RS-83277) shows similar activity by significantly enhancing the tumoricidal activity of human monocytes
TP1516 C-Reactive Protein (CRP) (77-82)

C-Reactive Protein (CRP) 77-82

C-Reactive Protein (CRP) 77-82 is the 77-82 fragment of C-Reactive Protein. C-Reactive Protein (CRP), the prototypic marker of inflammation, is a cardiovascular risk marker and may promote atherogenesis.C-reactive protein (CRP) is an annular (ring-shaped)
T11386L Gemcabene

PD-72953

Others Others
Gemcabene (PD-72953) 是一种具有抗炎活性的降脂剂。 Gemcabene 降低低密度脂蛋白胆固醇和甘油三酯,提高高密度脂蛋白胆固醇,并降低促炎急性期蛋白、C 反应蛋白。
T0825 Ebselen

SPI-1005,PZ-51,依布硒,CCG-39161

Phosphatase; Virus Protease; Calcium Channel; COX; HIV Protease Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Ebselen (CCG-39161) 是一种谷胱甘肽过氧化物酶模拟物,是电压依赖性钙通道阻断剂。它抑制Mpro 和COVID-19病毒,是HIV-1衣壳 CTD 二聚化的抑制剂,具有抗炎、抗癌和抗氧化活性。
T11386 Gemcabene calcium

PD-72953 calcium

Others Others
Gemcabene calcium , a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) andexerting anti-inflammatory activity, lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP).
T78639 Oxidized ATP trisodium salt

oATP trisodium salt

P2X Receptor Membrane transporter/Ion channel; Neuroscience
Oxidized ATP (oATP) trisodium salt 是一种P2 受体广泛抑制剂,其不可逆地阻断P2X7R活化并抑制CRP引发的NLRP3炎性体激活,常用于动脉粥样硬化研究。
T68297 Dilmapimod tosylate

Dilmapimod tosylate is a potent p38 mitogen-activated protein kinase (MAPK) inhibitor. It was investigated for its anti-inflammatory effect in non-head injury trauma patients at risk for developing acute respiratory distress syndrome. IL-1β was identified as a gene regulated by dilmapimod that could influence c-reactive protein levels. Dilmapimod had been in phase III clinical trials by GlaxoSmithKline for the treatment of rheumatoid arthritis, neuropathic pain, coronary artery disease (CAD) and...
T78732 BO-1

BO-1是一种苯甲酸酯类抗菌活性化合物。它能够抑制多重耐药金黄色葡萄球菌,同时与环丙沙星等抗生素显示协同效应。此外,BO-1可逆转该菌株的耐药性,并在小鼠体内降低IL-6及C反应蛋白的水平。
T74844 Antiproliferative agent-23

Antiproliferative agent-23,一种微管去稳定剂(MDA),通过扰乱微管蛋白-微管系统来发挥作用。该化合物通过降低Bcl-2蛋白水平、提高Bax和Cyt c蛋白水平以及激活半胱天冬酶级联反应和线粒体依赖途径来诱导细胞凋亡。此外,Antiproliferative agent-23还能在A549/CDDP细胞(顺铂耐药癌细胞系)中通过PERK/ATF4/CHOP信号通路激活ROS介导的内质网应激,展现出抗肿瘤活性。

化合物

C-Reactive Protein (CRP) 201-206 acetate
Cat.No: TP1676L
Synonym: C-Reactive Protein (CRP) 201-206 acetate(130348-99-1 free base)
Target: Others
C-Reactive Protein (CRP) 77-82 acetate
Cat.No: TP1516L
Synonym: C-Reactive Protein (CRP) 77-82 acetate(130349-01-8 free base)
Target: Others
C-Reactive Protein (CRP) 174-185 acetate
Cat.No: TP1592L
Synonym: C-Reactive Protein (CRP) 174-185 acetate(160369-86-8 free base)
Target: Others
C-Reactive Protein (CRP) (201-206)
Cat.No: TP1676
Synonym: C-Reactive Protein (CRP) 201-206
Target: Others
C-Reactive Protein (CRP) (174-185)
Cat.No: TP1592
Synonym: C-Reactive Protein (CRP) 174-185
Target:
C-Reactive Protein (CRP) (77-82)
Cat.No: TP1516
Synonym: C-Reactive Protein (CRP) 77-82
Target:
Gemcabene
Cat.No: T11386L
Synonym: PD-72953
Target: Others
Ebselen
Cat.No: T0825
Synonym: SPI-1005,PZ-51,依布硒,CCG-39161
Target: Phosphatase, Virus Protease, Calcium Channel, COX, HIV Protease
Gemcabene calcium
Cat.No: T11386
Synonym: PD-72953 calcium
Target: Others
Oxidized ATP trisodium salt
Cat.No: T78639
Synonym: oATP trisodium salt
Target: P2X Receptor
Dilmapimod tosylate
Cat.No: T68297
Synonym:
Target:
BO-1
Cat.No: T78732
Synonym:
Target:
Antiproliferative agent-23
Cat.No: T74844
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T2851 Daphnetin

7,8-Dihydroxycoumarin,Daphnetol,瑞香素

EGFR; PKA; PKC; Parasite; Autophagy Angiogenesis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
Daphnetin (7,8-Dihydroxycoumarin) 是从 Genus Daphne 中分离得到的香豆素衍生物,有抗氧化、抗炎、抗疟疾和解热作用,可用于凝血功能障碍、类风湿性关节炎等疾病的相关研究。
T5736 1,3-Dicaffeoylquinic acid

CYNARIN,1,3-二咖啡酰奎宁酸,Cyclohexanecarboxyli​c acid, 1,​3-​bis[[3-​(3,​4-​dihydroxyphenyl)​-​1-​oxo-​2-​propen-​1-​yl]​oxy]​-​4,​5-​dihydroxy-​, (1S,​3R,​4R,​5R)​-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid

Reactive Oxygen Species; Akt; PI3K Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
1,3-Dicaffeoylquinic acid (CYNARIN) 是一种咖啡酰奎宁酸衍生物,具有抗氧化、自由基清除作用。
T35624 Ajoene

Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs = 5-160 &#181g/ml) and Gram-negative bacteria (MICs = 136-200 &#181g/ml), as well as yeasts (MICs = 10-20 &#181g/ml).1Ajoene is cytotoxic to mouse melanoma cells (IC50= 18 &#181M), as well as human colon, lung, mammary, and pancreatic cancer cells (IC50s = 7-41 &#181M).2It reduces...

天然产物

Daphnetin
Cat.No: T2851
Synonym: 7,8-Dihydroxycoumarin,Daphnetol,瑞香素
Target: EGFR, PKA, PKC, Parasite, Autophagy
1,3-Dicaffeoylquinic acid
Cat.No: T5736
Synonym: CYNARIN,1,3-二咖啡酰奎宁酸,Cyclohexanecarboxyli​c acid, 1,​3-​bis[[3-​(3,​4-​dihydroxyphenyl)​-​1-​oxo-​2-​propen-​1-​yl]​oxy]​-​4,​5-​dihydroxy-​, (1S,​3R,​4R,​5R)​-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid
Target: Reactive Oxygen Species, Akt, PI3K
Ajoene
Cat.No: T35624
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-03363 C-Reactive Protein Protein, Human, Recombinant

C-Reactive Protein,C-rea...

Human HEK293 Cells
C-Reactive Protein Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1.
TMPY-02047 C-Reactive Protein Protein, Rat, Recombinant (His)

C-reactive protein, pentraxin-rel...

Rat HEK293 Cells
C-Reactive Protein Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.6 kDa and the accession number is H6X2V1.
TMPK-00114 C-Reactive Protein /CRP Protein, Human, Recombinant (His)

C-reactive protein,MGC88...

Human HEK293 Cells
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate immunity, opsonization by its properties, complement activation and immunoglobulins receptor binding. CRP is a protein of the acute systemic inflammation and is, therefore, a prime marker of inflammation.The CRP is quantified by immunonephelometry or immunoturbidimetry. C-Reactiv...
TMPY-05336 C-Reactive Protein Protein, Human, Recombinant, Biotinylated

C-Reactive Protein,PTX1,C

Human HEK293 Cells
C-Reactive Protein Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1.
TMPY-06937 C-Reactive Protein Protein, Human, Recombinant (His & Avi), Biotinylated

C-Reactive Protein,PTX1,C

Human HEK293 Cells
C-Reactive Protein Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 26.3 kDa and the accession number is P02741-1.
TMPY-01581 C-Reactive Protein Protein, Mouse, Recombinant (His)

C-reactive protein, pentraxin-rel...

Mouse HEK293 Cells
C-Reactive Protein Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.4 kDa and the accession number is P14847.
TMPK-01333 C-Reactive Protein /CRP Protein, Cynomolgus, Recombinant (His)

C-reactive protein,pentraxin 1,PT...

Cynomolgus HEK293 Cells
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate immunity, opsonization by its properties, complement activation and immunoglobulins receptor binding. CRP is a protein of the acute systemic inflammation and is, therefore, a prime marker of inflammation.The CRP is quantified by immunonephelometry or immunoturbidimetry. C-Reactiv...
TMPH-02681 GPX7 Protein, Mouse, Recombinant (His & Myc)

Mouse E. coli
It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks. GPX7 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 26.7 kDa and the accession number is Q99LJ6.
TMPH-00099 NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)

Arabidopsis thaliana P. pastoris (Yeast)
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Plays a role in response to reactive oxygen species (ROS) stress. NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in yeast with N-10xHis and C-Myc tag. The predicted molecular weight is 20.5 kDa and the accession number is P39207.
TMPK-00493 OSMR Protein, Cynomolgus, Recombinant (His)

OSMR,IL-31R-β,PLCA1,IL-31RB,OSMRBMGC150626...

Cynomolgus HEK293 Cells
OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death. OSMR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted ...
TMPK-00571 OSMR Protein, Canine, Recombinant (His)

OSMRB,IL-31R-β,OSMR,OSMRBMGC150626,OSMR β,IL-31R su...

Canine HEK293 Cells
OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death. OSMR Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted mole...
TMPY-00055 LCAT Protein, Human, Recombinant (His)

lecithin-cholesterol acyltransfer...

Human HEK293 Cells
Lecithin: cholesterol acyltransferase (LCAT) is the sole enzyme that esterifies cholesterol in plasma, thus determining the maturation of high-density lipoproteins. Because it maintains an unesterified cholesterol gradient between peripheral cells and extracellular acceptors, for a long time, LCAT has been considered as a key enzyme in reverse cholesterol transport. Lecithin cholesterol acyltransferase (LCAT) plays a pivotal role in HDL metabolism.LCAT is intimately involved in HDL maturation an...
TMPY-01816 Pentraxin 3 Protein, Human, Recombinant (His)

TNFAIP5,pentraxin 3,PTX3,TSG-14

Human HEK293 Cells
Pentraxin-related protein PTX3, also known as Tumor necrosis factor alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, PTX3 and TNFAIP5, is a secreted protein that contains one pentaxin domain. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. Pentraxins are a family of evolutionarily conserved multifunctional pattern-recognition proteins characterized by a cycl...
TMPK-01450 HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

KRAS1,MHC,K-RAS4B,KRAS,CFC2,K-RAS...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01456 HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)

KRAS2,NS,MHC,C-K-RAS,KRAS1,K-RAS2A,K-RAS2B...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01451 HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)

NS3,K-RAS4A,K-Ras 2,NS,KRAS1,RASK2,MHC,KI-RAS,KRAS,...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.

重组蛋白

C-Reactive Protein Protein, Human, Recombinant
Cat.No: TMPY-03363
Species: Human
Expression System: HEK293 Cells
C-Reactive Protein Protein, Rat, Recombinant (His)
Cat.No: TMPY-02047
Species: Rat
Expression System: HEK293 Cells
C-Reactive Protein /CRP Protein, Human, Recombinant (His)
Cat.No: TMPK-00114
Species: Human
Expression System: HEK293 Cells
C-Reactive Protein Protein, Human, Recombinant, Biotinylated
Cat.No: TMPY-05336
Species: Human
Expression System: HEK293 Cells
C-Reactive Protein Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06937
Species: Human
Expression System: HEK293 Cells
C-Reactive Protein Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01581
Species: Mouse
Expression System: HEK293 Cells
C-Reactive Protein /CRP Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01333
Species: Cynomolgus
Expression System: HEK293 Cells
GPX7 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02681
Species: Mouse
Expression System: E. coli
NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
Cat.No: TMPH-00099
Species: Arabidopsis thaliana
Expression System: P. pastoris (Yeast)
OSMR Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00493
Species: Cynomolgus
Expression System: HEK293 Cells
OSMR Protein, Canine, Recombinant (His)
Cat.No: TMPK-00571
Species: Canine
Expression System: HEK293 Cells
LCAT Protein, Human, Recombinant (His)
Cat.No: TMPY-00055
Species: Human
Expression System: HEK293 Cells
Pentraxin 3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01816
Species: Human
Expression System: HEK293 Cells
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01450
Species: Human
Expression System: HEK293 Cells
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01456
Species: Human
Expression System: HEK293 Cells
HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01451
Species: Human
Expression System: HEK293 Cells
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